The skin is the biggest organ in the body, and it covers the entire body. It acts as a barrier against heat, light, injury, and infection. Its main functions are protection, thermal regulation, and sensation. The epidermis, dermis, and subcutaneous layer are the three primary layers of the skin.

Skin Injuries and Wound

Skin injuries can occur anywhere on the body. It comprises wounds, scratches, scrapes, bruises, and swelling. Wounds recover in stages. The smaller the wound, the faster it heals. The greater or deeper the wound, the longer it will take to heal. When the skin is injured, numerous skin cell types within these three layers collaborate at specific stages to repair.

Types of Skin Injuries

Skin injuries are divided into three major group, which are listed below.

• Cuts, lacerations, gashes, and tears: These are wounds that penetrate the skin and reach the fat tissue. The result of a sharp object.
• Scrapes, abrasions, scratches, and floor burns: These are superficial wounds that do not penetrate the skin. Scrapes on the knees, elbows, and palms are common.
• Bruises: These are caused by damaged blood vessels leaking into the skin. Caused by a sprain or any other type of injury. They can occur in the absence of a cut or scrape.

Wound Healing Stages

The skin healing stages of hemostasis, inflammation, angiogenesis, growth, re-epithelialization, and remodeling occur in a temporal sequence but also overlap.^[1] Thus, skin repair is among the most complex processes in the human body.

Factors Affecting Wound Healing Process

A variety of factors influence the wound healing process. The following are the most important and common factors:

Environmental Factors in the Wound Healing Process

• Irritation Free Skin: It is important to calm wound tissues so that irritation does not interfere with the healing process. To relax the skin tissues, avoid using any chemical or drug based wound healing products; instead, use more natural products that provide an optimal soothing environment for faster and natural healing.
• Cell Nourishment: For optimal healing, healing cells must be properly nourished with natural minerals and enzymes, such as those found in Red Sea salt, so that they can work effectively.
• Infection Control: When an infection exists, the cells’ ability to repair properly and naturally is hampered. It is critical to keep the skin free from infection by using natural methods such as natural enzyme, lysozyme based products.
• Moist Natural Environment: Wounds heal faster and less painfully in a moist natural environment than in a dry setting, where cells normally dehydrate and die.
• Oxygenation and Pressure: When there is excessive or continuous pressure at the wound site, the blood supply to the capillary network may be disrupted. This reduces blood flow to the surrounding tissue and delays and hence slows recovery.
• Trauma and Oedema: Wounds heal slowly and may not heal completely if they are repeatedly traumatized or deprived of local blood supply by oedema.

Systemic Factors in the Wound Healing Process

Wound healing can be slowed by systemic factors that have little or no direct relationship to the location of the wound. Age, body type, chronic disease, immunosuppression, nutritional state, radiation therapy, and vascular insufficiencies are among them.

Role of Salt in Wound Healing Process

Since ancient times, salt has been used as a medicinal agent in dermatological problems. Though it is a popular agent in both traditional and modern medicine, it is crucial to understand its relationship to the skin to maximize the overall effect.^[2]

Best Sea Salt For Wound Healing Management

It is critical to understand the source, extraction procedures, and processing techniques of the salt because all these factors have a significant impact on the therapeutic properties of the salt.

Sodium Chloride: Chemically Processed, Weak, and Slow

It is also known as common salt, and it is extracted commercially using rusting machinery during the extraction process, and it is heavily treated with chemicals and at high temperatures for commercial manufacture. Because it only contains two components, sodium and chloride, common salt is very weak in terms of therapeutic capabilities because it lacks all of nature’s major trace elements.

Sea Salt: Natural, Mineral Rich, and Fast Acting

Sea salt is obtained by evaporating seawater, as its name suggests. The resulting salt is minimally processed or left unprocessed, allowing it to retain trace minerals including calcium, potassium, iron, zinc, bromide, and magnesium etc., which play beneficial role in wound healing process.

The Best Sea Salt for Human Health is the Red Sea Salt

Among all the sea salts, Red Sea salt is the best sea salt for human health because its mineral content matches the human saline system. The Red Sea is one of the most saline water bodies in the world because of the water circulation pattern resulting from evaporation and wind stress. The Red Sea holds one of the world’s most rich and diverse ecosystems.

Red Sea salt is unrefined and hand harvested from the Red Sea and is one of the most mineral rich sea salts available in the world today. It contains over 82 trace minerals such as sodium, chloride, calcium, potassium, manganese, zinc, copper, silver, iron, and iodine, etc. that are essential for optimal healing as well as nourishing the skin naturally.

Scientific Data on Sea Salt in Wound Healing Management

Therapeutic properties

The scientific literature highlighted the importance of minerals in salt that interact with skin and the benefits associated with these minerals. It also emphasizes that the mineral contents of the salt are very important for its therapeutic properties.^[3]

Wound Healing properties

The use of Red Sea salt based sprays for diabetic foot ulcer management has been studied and has provided significant beneficial results in foot ulcer healing.^[4]

Wound Healing Accelerators

Scientific literature has recognized minerals as wound healing accelerators, along with vitamins and growth factors that take an active part in the healing process.^[5]

Aesthetic and Reconstructive Surgery Healing

A Clinical study in aesthetic medicine confirms the safety and high potential of sea salt based facials in treating aging skin, acne, infection, edema, and wound healing. The post surgical infection patients in the sea salt group showed uniform rapid resolution of infection, inflammation, erythema, and pain and accepted wound care.^[6]

Activate the Healing Process

Saltwater rinses inducing vasodilation and lowering the bacterial load, simplifying phagocytes to the injury site, alkalizing saliva, and acting as an astringent.^[7]

Scientific Data on Lysozyme in Wound Healing Management

Natural Antibacterial Activity

A study confirms that a moisture balanced antibacterial dressing loaded with lysozyme possesses antibacterial activity and promotes wound healing.^[8]

Promotes Tissue Regeneration

Experiments demonstrated that biomaterials composed of lysozyme loaded CS–EDTA nanofibers have a strong potential for wound healing.^[9]

Strong Potential for Antibacterial Resistant Healing

 Lysozyme demonstrated significant application potential in the prevention and treatment of S.aureus infections, as well as scalded wound healing. The most noteworthy finding in this study is the unexpectedly powerful inhibitory effect of lysozyme on drug resistant bacteria, particularly MRSA, which is extremely hard to treat with standard antibacterial medications.^[10]

Promote Cutaneous Wound Healing

Several studies have confirmed the unique applicability of lysozyme in the healing process of various wound injuries. The phase transited lysozyme PTLG multifunctional hydrogel is a promising multifunctional dressing material that might meet the diverse demands of complex and deep wounds.^[11]

Epithelial Growth for faster Healing

The translucent balsa modified lysozyme dressing has high antibacterial capabilities, stable and sustained release, no cytotoxicity, and the potential to stimulate antibacterial ability, epithelial growth, cell proliferation, and migration.^[12]

Ocean Aid: Leading Skin and Wound Care Company

Ocean Aid products, Oceanzyme Spray, and Oceanzyme Foam offer a comprehensive spectrum of treatments ranging from tiny scrapes and cuts to difficult to heal chronic wounds. Ocean Aid is constantly innovating through research and development to create all natural products for chronic and acute wound healing problems.

Ocean Aid Products: Natural Wound Care Innovation and Excellence

Ocean Aid is the world’s first company to combine lysozyme and Red Sea salt to provide a very effective natural scientific solution for wound care management. This patented scientific formulation of natural components not only heals but also moisturizes the wound, improving the functionality and vitality of healing cells.

Ocean Aid Products: Wide Range of Applications

Ocean Aid products provide the most extensive and successful range of healing solutions for pressure ulcers, leg ulcers, diabetic foot ulcers, burns, scars, post surgery, shingles, skin rashes, cuts, scrapes, psoriasis, athletes foot, blisters, insect bites, poison ivy, acne, sunburns, nasal spray, and canker sores.

Wound Healing Mechanism in Ocean Aid Products

The formula’s enzyme barrier works with the human immune system to help protect the body and continues working for 4 to 5 hours after initial use. The natural sea salt used in the formula contains 82 trace elements and minerals that help nourish the cells. The enzyme action combined with the elements and minerals from the sea salt create an optimal environment by helping to nourish the healing cells. By replicating the optimal pH balance and salinity of the body, Ocean aid is safe for all ages and skin types.

Ocean Aid Products: Approved by Professionals

Ocean Aid Products: Clinically Studied

Ocean Aid products have been scientifically tested and studied in clinical research that proves their efficacy in diabetic foot ulcer management. The study opens the door for a unique, new natural therapy to aid in daily wound care.^[13]

Ocean Aid Products: All Natural and Effective

Ocean Aid products are all natural and do not contain any drugs, chemicals, colors, preservatives, and do not cause any burning sensations when applied to wounds. This entire process calms the tissue and speeds up the healing process.

Acute and Chronic Wound Management with Ocean Aid Products

There is considerable evidence in the medical literature that shows how wound infections continue to be a major concern because to biofilm colonization, delayed healing, and drug resistance.^[14]

Ocean Aid Spray and Ocean Aid Foam nourish the healing cells with natural ingredients from Red Sea salt, clean the wound with antibacterial action of lysozyme, and help the healing cells operate at their best. Because it is 100% natural, the entire healing process is healthier, faster, and pain free. Ocean Aid products can be used frequently because there is no risk of medication resistance, making them unique and strong, particularly for aiding in the treatment of chronic wound healing.

Ocean Aid Products with Eco Friendly Packaging

Ocean Aid revolutionary technique utilized in the container of Ocean Aid Spray protects the sterile solution from airborne microorganisms. All packaging materials require less material and are recycled to protect the environment’s health.

Conclusion

Ocean Aid’s all natural healing and wound care management products, Oceanzyme Spray and Oceanzyme Foam, contains two natural yet strong ingredients, Red Sea salt and Lysozyme, that work together to significantly aid the healing process. Ocean Aid products not only promote faster wound healing recovery but also healthy healing without any complications.

References

1. Gurtner GC, Werner S, Barrandon Y, Longaker MT. Wound repair and regeneration. Nature 453: 314–321, 2008.
2. Manoharan, P. and Kaliaperumal, K. (2022), Salt and skin. Int J Dermatol, 61: 291-298.
3. Polefka, T.G., Bianchini, R.J. and Shapiro, S. (2012), Interaction of mineral salts with the skin: a literature survey. Int J Cosmet Sci, 34: 416-423
4. Pougatsch DA, Rader A, Rogers LC. The Use of a Sea Salt-based Spray for Diabetic Foot Ulcers: A Novel Concept. Wounds: A Compendium of Clinical Research and Practice. 2017 Feb;29(2):E5-E9
5. Boateng JS, Matthews KH, Stevens HN, Eccleston GM. Wound healing dressing and drug delivery systems: A Review. J Pharmaceutical Sci 2008; 97: 8: 2892-2923
6. Chernoff G (2021) A Novel Combination Therapy in Aesthetic and Reconstructive Surgery: Sea Salt, Exfoliation, Cavitating Ultrasound, and High Intensity Multiwavelength LED Treatment: (SaltFacial). J Clin Cosmet Dermatol 5(2).
7. Hoover, E. Tovar, T. Zlatnik, and C. Karunanayake, “Efficacy of a rinse containing sea salt and lysozyme on biofilm and gingival health in a group of young adults: a pilot study,” International Journal of Dentistry, vol. 2017.
8. Xiao, L., Ni, W., Zhao, X., Guo, Y., Li, X., Wang, F., Luo, G., Zhan, R., & Xu, X. (2021). A moisture balanced antibacterial dressing loaded with lysozyme possesses antibacterial activity and promotes wound healing. Soft matter.
9. Charernsriwilaiwat N et al. Lysozyme-loaded, electrospun chitosan-based nanofiber mats for wound healing. I J Pharmaceutics 2012;427 (2): 379-384.
10. Chen LL et al. Antibacterial activity of lysozyme-loaded cream against MRSA and promotion of scalded wound healing. I J Pharmaceutics 2022; 122200.
11. Chen J et al. Converting lysozyme to hydrogel: A multifunctional wound dressing that is more than antibacterial. Colloids and Surfaces B: Biointerface 2022; 219: 112854.
12. Daijun Zhou, Tao Yang, Wei Qian, Malcolm Xing & Gaoxing Luo (2019) Study of the mechanism of environmentally friendly translucent balsa-modified lysozyme dressing for facilitating wound healing, International Journal of Nanomedicine, 13:, 4171-4187.
13. Pougastch DA, Rader A, Rogers LC. The Use of a Sea Salt-based Spray for Diabetic Foot Ulcers: A Novel Concept. Wounds 2017; 29(2): E5-E9.
14. Ding X, Tang Q, Xu Z, Xu Y, Zhang H, Zheng D, Wang S, Tan Q, Maitz J, Maitz PK, Yin S, Wang Y, Chen J. Challenges, and innovations in treating chronic and acute wound infections: from basic science to clinical practice. Burns Trauma. 2022 May 21;10: tkac014.